Polymethyl methacrylate (PMMA) has been one of the most established polymers in dental prosthetics for decades. Traditionally, it has been primarily used for denture bases and provisional restorations. However, the digitalization of dentistry—particularly the adoption of CAD/CAM systems—has significantly expanded both the range of applications and the quality level of PMMA. Today, milled PMMA restorations achieve a level of precision and mechanical stability that conventionally polymerized materials rarely offer—an advantage that is increasingly reflected in the daily workflows of dental laboratories, in-house practice labs, and milling centers.
With the transition from manual processing to industrially polymerized PMMA blanks, both the mechanical properties and clinical success parameters have evolved. Studies show that CAD/CAM-milled PMMA bases exhibit lower porosity, higher flexural strength, and better material homogeneity than heat-polymerized alternatives (Joda et al., 2021). At the same time, new indication areas have emerged, such as occlusal splints, long-term esthetic provisionals, and temporary implant-supported prosthetics.
This article provides a scientifically grounded overview of PMMA material science, clinical indications, and the advantages of digitally milled PMMA restorations. The analysis is based on systematic reviews, in vitro studies, and well-established review articles and is intended for users who wish to optimize their manufacturing strategies or make informed decisions regarding material selection.
